Progesterone's Many Roles:
* Precursor of other sex hormones (oestrogen and testosterone) and cortisone
* Maintains lining of the uterus
* Promotes the survival of the embryo and foetus throughout gestation
* Protects against fibrocystic breasts * Natural diuretic thus helping to control fluid balance
* Promotes fat burning for energy (thermogenesis)
* Acts as a natural anti-depressant
* Aids thyroid hormone action
* Normalizes blood clotting by off-setting the excess fibrin formation from the action of Estrogens
* Maintains sex drive
* Keeps blood sugar levels normal
* Normalizes zinc and copper levels
* Promotes proper cell oxygen levels for enhanced energy
* Protects against endometrial cancer
* Helps protect against breast cancer
* Promotes bone building and protects against osteoporosis
Manufacturing Issues & Industry Facts
Natural progesterone is derived from the culturing process done on wild yam or soy that contains the steroid precursor, diosgenin. The hormone is poured off and sprayed onto generally rice powder to stabilize. Hormone powders in general tend to have a 1/2 life of 90 days, so the fresher the raw material is, the better. OTC product that is mixed in large vats and then bottled can sometimes be 2-3 years old by the time the customer gets it. This is why we like the Pregest product since the manufacturer takes the time to get the date-of-manufacture (DOM), not the date of bottling. Progesterone scripts given by physicians are typically given orally in much higher doses because they know it has to be partially destroyed by the liver (first pass) and you end up with generally less than 10% of the oral dose being available for the body. We highly discourage oral hormone use of any kind since the first-pass throughthe liver up over time can cause chronic hepatitis which can eventually lead to cancer later in life. We prefer topical creams or gels, sublingual pellets, vaginal suppositories
Benefits: These non-oral delivery methods avoid liver first-pass altogether. Also, less hormone is required if transdermal is ued since it is stored in the fat tissues which essentially makes it timed release dosing which is more consistent. Progesterone restoration occurs rapidly with transdermal except for those who are especially deficient in progesterone, for whom, it may take two or three months to restore optimal levels.
Warning: Progesterone is a hormone which can be converted by the body into other hormones. Each person is different. Women of normal or excess bodyweight will tend to convert more into Estrogens, and should be checked via Saliva Hormone Test periodically. Also, if excess Estrogens are an issue, use of natural anticlotting compounds in like Krill Oil, Salmon, etc. should be eaten. Excess Progesterone levels can cause the following (if it stays as Progesterone) Loose ligaments, therefore structual issues like back problems, sprained ankles, etc. (remember one of it's job is to get the body ready to deliver a baby..) Excess Sleepiness Excess bloating, sore breasts if it is converting more into estrogens... Agressiveness and Moodiness and facial hair if converted into testosterone Unusal Bleeding and heavier menstruation. Remedy: Stop using the progesterone. It takes approx. 90 days to clear from tissues. Contact your healthcare professional to discuss what is happening and consider a FDA-approved Saliva Test to determine tissue levels.
References 1 Hargrove JT, Maxson WS, Wentz AC, Burnett LS. Menopausal hormone replacement therapy with continuous daily oral micronized estradiol and progesterone. Obstet Gynecol. 1989;73:606 612. 2 Barnard ND. Natural progesterone: Is oestrogen the wrong hormone? An interview with John R. Lee, MD. Good Health. 1994;Spring. 3 Prior JC. Progesterone as a bone-trophic hormone. Endocrine Reviews. 1990;11:386-398. 4 Lee JR. What Your Doctor May Not Tell You About Menopause. New York: Warner Books; 1996. 5 Lee JR. Is natural progesterone the missing link in osteoporosis prevention and treatment? Medical Hypotheses. 1991;35:316-318. 6 The Writing Group for the PEPI Trial. Effects of oestrogen or oestrogen/progestin regimens on heart disease risk factors in postmenopausal women. JAMA. 1995;273:199-208. 7 Estratab (esterified oestrogen tablets). Product Information. Physicians' Desk Reference: Medical Economics; 1996 8 Archives Journal Club/Women's Health. Oestrogen replacement therapy and heart disease: A discussion of the PEPI trial. 1995
Serving Size: 1/8-1/2 teaspoon depending on application end use
1/4 teaspoon = 1.25 grams
No.Servings per Container: 56 grams
USP Progesterone 1.6% by weight 506 mg. per oz./ 1012 mg. per 2 oz. jar 1/4 tsp. = 20 mg. per dose
In a Proprietary Blend of: Aloe Vera Extract in Distilled Water with Catalyst Altered Normalizer, Octyl Palmitate (palm vitamin A) Tocopheryl Acetate (vitamin E), Glycerin Stearic Acid, Glyceryl Stearate Natural Wild Yam Extract, Cetyl Alcohol, Oleic Acid Hazel Nut Oil, Grape Seed Oil Panthenol (B5), Grape Seed Extract Triethanolamine, Sodium Hyaluronate (Hyaluronic Acid--HA) Carbomer, Potassium Sorbate Methylparaben (fruit wax preservative) Phenoxyethanol (alcohol preservative) Fragrance HYPOALLERGENIC. NO SOY, GLUTEN, EGG, DAIRY PRODUCTS.

 Use Instrucions: 1/8 to1/4 teaspoon per dose in a.m. or as directed by professional, 5 days on, 2 off. Discontinue during Menses. Rub into thin skinned area like the forearms. Rotate area every use. Do not rub into heavily fatty areas like the abdomen or the thighs or buttocks. CAUTION: DISCONTINUE IF ADVERSE EFFECTS OCCUR.


Date of Manufacture rather than Date of Packaging given as Exp.Date to insure hormone activity. Product has a 6 mos. shelf life once opened if stored in cool dry place.

Cost: $31.95 per 2 oz. jar

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